As Matchday 21 matches take center stage across eight sites on Tuesday, April 1, and Wednesday, April 2, 2025, the Ghana Premier League is expected to resume with a frenzy of action.
Following a short break, the league is back with a full midweek schedule that includes relegation fights, title-chasing matches, and regional derbies. Fans will be treated to some of the season’s most anticipated games, as important teams compete for vital points in their individual pursuits.
With both teams aiming for a serious run at the championship, the Western derby between Medeama and Basake Holy Stars is one of the major events of the midweek action. At the T&A Stadium in Tarkwa, Medeama, who are currently contending for the top spot, will play their neighbors with the goal of securing a crucial three points to maintain their title chances.
In addition, Gold Stars FC, in second position, will host Heart of Lions at Duns Park in Bibiani on Tuesday. The Gold Stars will try to keep up their momentum and put more pressure on the league leaders, Asante Kotoko, who are right in their sights.

In the meanwhile, Kotoko will play on Wednesday when they visit Kumasi’s Baba Yara Stadium to face Berekum Chelsea. Kotoko wants to increase their lead at the top of the table, thus this high-stakes match could be crucial in the title chase.
With six games scheduled across the nation, Wednesday’s program is as full. One of Ghana’s best-known teams, Hearts of Oak, will finally return to the Accra Sports Stadium to face Nations FC.
Hearts of Oak is hoping to recover from recent losses, thus this game could be an exciting spectacle. In other news, Karela United, who are fighting to stay in the league, will play struggling Legon Cities at the Aliu Mahama Sports Stadium in a game that might have a big impact on both teams’ chances of surviving.
A variety of teams, some riding high on confidence and others hoping to bounce back from recent setbacks, are featured in the midweek matchups. For example, in an attempt to improve their previous bad performance, Vision FC will play FC Samartex 1996, the reigning champions, at the Nii Adjei Kraku II Sports Complex in Tema.
Dreams FC, who have been revitalized after a string of outstanding games, will have a difficult challenge against Bechem United at the Tuba AstroTurf. With the relegation battle escalating and the title race heating up, Matchday 21 promises to be filled with exciting matches and pivotal moments that could determine the course of the season.